KMID : 0388120050140040228
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Journal of Korean Society for the Study of Obesity 2005 Volume.14 No. 4 p.228 ~ p.234
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White Blood Cell Count is Higher in Women with Metabolic Syndrome: National Health and Nutrition Examination Survey of Korea
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Kim Jeong-A
Kim Sun-Mee Choi Youn-Seon Yoon Do-Kyung
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Abstract
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Objective: In order to characterize the association between metabolic syndrome (MS) and inflammation, this
study has focused on a delineation of the relationship existing between white blood cell (WBC) counts and MS, as defined by the International Diabetes Federation.
Methods: A total of 3,279 non-alcoholic, non-smoking adult women from the 1998 Korean National Health and
Nutrition Survey (KNHNS) were included in this analysis. The KNHNS is a cross-sectional health survey taken with
a nationally representative sample of the Korean population. Trained interviewers conducted interview, anthropometric, blood pressure and laboratory tests measurement.
Results: Waist circumference, triglycerides (TG), and fasting plasma glucose (FPG) were found to be increased
(p for linearity = 0.0491 in waist circumference; < 0.0001 in TG; 0.0002 in FPG) and high density lipoprotein cholesterol (HDL-C) was shown to decrease, with increases in the WBC count (p for linearity = 0.0225). Subjects with lower HDL-C, higher TG, and higher FPG also evidenced higher WBC counts ( P= 0.0006 in HDL cholesterol; P< 0.0001 in TG; P= 0.0051 in FPG). The risk for clustered MS components was increased along with increasing WBC counts ( Pfor trend < 0.001). WBC
counts were higher in MS patients than in non-MS person after adjustments were made for age ( P= 0.00008).
Conclusion: WBC counts were elevated in female MS subjects. This result suggests that increased WBC counts,
even within a clinically normal range, might constitute another feature of MS, and might potentially prove useful as an indicator of cardiovascular risk.
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KEYWORD
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International Diabetes Federation, IDF, Metabolic syndrome, White blood cell
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